multiple central giant cell granuloma of the mandible: a case report

Authors

ali lotfi

department of oral & maxillofacial pathology, shahid beheshti university of medical sciences, dental faculty, tehran, iran saede atarbashi moghadam

department of oral & maxillofacial pathology, shahid beheshti university of medical sciences, dental faculty, tehran, iran fazele atarbashi moghadam

department of periodontics, shahid sadoughi university of medical sciences, dental faculty, yazd, iran

abstract

introduction: central giant cell granuloma is a benign lesion but sometimes has aggressive proliferation composed of multinucleated giant cells in a background of spindle and ovoid mesenchymal cells. multifocal central giant cell granuloma of jaws is very rare and usually associated with hyperparathyroidism and some syndromes. we described an un-usual case of a 22-year-old man with idi-opathic multiple central giant cell granuloma of mandible without significant clinical find-ings. the parathyroid hormone level, calcium and phosphorus inorganic were in normal limit. patient had no familial history and clinical characteristic of cherubism, noonan-like syndrome and neurofibromatosis. this article refers to the fact that multiple central giant cell granuloma may be associated with no signs of systemic or specific syndromes and it can be an independent and idiopathic disease.

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Journal title:
journal of dentomaxillofacil radiology, pathology and surgery

جلد ۲، شماره ۱، صفحات ۲۸-۳۱

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